Impact of Apolipoprotein(a) Isoform Size on Lipoprotein(a) Lowering in the HPS2-THRIVE Study

BACKGROUND: Genetic studies have shown lipoprotein(a) (Lp[a]) to be an important causal risk factor for coronary disease. Apolipoprotein(a) isoform size is the chief determinant of Lp(a) levels, but its impact on the benefits of therapies that lower Lp(a) remains unclear. METHODS: HPS2-THRIVE (Heart...

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Detalles Bibliográficos
Autores principales: Parish, Sarah, Hopewell, Jemma C., Hill, Michael R., Marcovina, Santica, Valdes-Marquez, Elsa, Haynes, Richard, Offer, Alison, Pedersen, Terje R., Baigent, Colin, Collins, Rory, Landray, Martin, Armitage, Jane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841847/
https://www.ncbi.nlm.nih.gov/pubmed/29449329
http://dx.doi.org/10.1161/CIRCGEN.117.001696

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841847/
https://www.ncbi.nlm.nih.gov/pubmed/29449329
http://dx.doi.org/10.1161/CIRCGEN.117.001696

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