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Particulate matter disrupts human lung endothelial cell barrier integrity via Rho-dependent pathways

Increased exposure to ambient particulate matter (PM) is associated with elevated morbidity and mortality in patients with cardiopulmonary diseases and cancer. We and others have shown that PM induces lung microvascular barrier dysfunction which potentially enhances the systemic toxicity of PM. Howe...

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Detalles Bibliográficos
Autores principales: Wang, Ting, Shimizu, Yuka, Wu, Xiaomin, Kelly, Gabriel T., Xu, Xiaoyan, Wang, Lichun, Qian, Zhongqing, Chen, Yin, Garcia, Joe G.N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841899/
https://www.ncbi.nlm.nih.gov/pubmed/28644070
http://dx.doi.org/10.1086/689906