Single-Cell Droplet Microfluidic Screening for Antibodies Specifically Binding to Target Cells

Monoclonal antibodies are a main player in modern drug discovery. Many antibody screening formats exist, each with specific advantages and limitations. Nonetheless, it remains challenging to screen antibodies for the binding of cell-surface receptors (the most important class of all drug targets) or...

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Detalles Bibliográficos
Autores principales: Shembekar, Nachiket, Hu, Hongxing, Eustace, David, Merten, Christoph A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842027/
https://www.ncbi.nlm.nih.gov/pubmed/29466744
http://dx.doi.org/10.1016/j.celrep.2018.01.071

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842027/
https://www.ncbi.nlm.nih.gov/pubmed/29466744
http://dx.doi.org/10.1016/j.celrep.2018.01.071

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