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Single-Cell Droplet Microfluidic Screening for Antibodies Specifically Binding to Target Cells
Monoclonal antibodies are a main player in modern drug discovery. Many antibody screening formats exist, each with specific advantages and limitations. Nonetheless, it remains challenging to screen antibodies for the binding of cell-surface receptors (the most important class of all drug targets) or...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842027/ https://www.ncbi.nlm.nih.gov/pubmed/29466744 http://dx.doi.org/10.1016/j.celrep.2018.01.071 |