Pharmacological Inhibition of Necroptosis Protects from Dopaminergic Neuronal Cell Death in Parkinson’s Disease Models

Dysfunctions in mitochondrial dynamics and metabolism are common pathological processes associated with Parkinson’s disease (PD). It was recently shown that an inherited form of PD and dementia is caused by mutations in the OPA1 gene, which encodes for a key player in mitochondrial fusion and struct...

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Detalles Bibliográficos
Autores principales: Iannielli, Angelo, Bido, Simone, Folladori, Lucrezia, Segnali, Alice, Cancellieri, Cinzia, Maresca, Alessandra, Massimino, Luca, Rubio, Alicia, Morabito, Giuseppe, Caporali, Leonardo, Tagliavini, Francesca, Musumeci, Olimpia, Gregato, Giuliana, Bezard, Erwan, Carelli, Valerio, Tiranti, Valeria, Broccoli, Vania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842028/
https://www.ncbi.nlm.nih.gov/pubmed/29466734
http://dx.doi.org/10.1016/j.celrep.2018.01.089

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842028/
https://www.ncbi.nlm.nih.gov/pubmed/29466734
http://dx.doi.org/10.1016/j.celrep.2018.01.089

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