Macrophage-Derived Extracellular Succinate Licenses Neural Stem Cells to Suppress Chronic Neuroinflammation

Neural stem cell (NSC) transplantation can influence immune responses and suppress inflammation in the CNS. Metabolites, such as succinate, modulate the phenotype and function of immune cells, but whether and how NSCs are also activated by such immunometabolites to control immunoreactivity and infla...

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Detalles Bibliográficos
Autores principales: Peruzzotti-Jametti, Luca, Bernstock, Joshua D., Vicario, Nunzio, Costa, Ana S.H., Kwok, Chee Keong, Leonardi, Tommaso, Booty, Lee M., Bicci, Iacopo, Balzarotti, Beatrice, Volpe, Giulio, Mallucci, Giulia, Manferrari, Giulia, Donegà, Matteo, Iraci, Nunzio, Braga, Alice, Hallenbeck, John M., Murphy, Michael P., Edenhofer, Frank, Frezza, Christian, Pluchino, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842147/
https://www.ncbi.nlm.nih.gov/pubmed/29478844
http://dx.doi.org/10.1016/j.stem.2018.01.020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842147/
https://www.ncbi.nlm.nih.gov/pubmed/29478844
http://dx.doi.org/10.1016/j.stem.2018.01.020

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