The potential of P2X7 receptors as a therapeutic target, including inflammation and tumour progression

Seven P2X ion channel nucleotide receptor subtypes have been cloned and characterised. P2X7 receptors (P2X7R) are unusual in that there are extra amino acids in the intracellular C terminus. Low concentrations of ATP open cation channels sometimes leading to cell proliferation, whereas high concentr...

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Detalles Bibliográficos
Autores principales: Burnstock, Geoffrey, Knight, Gillian E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2017
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842154/
https://www.ncbi.nlm.nih.gov/pubmed/29164451
http://dx.doi.org/10.1007/s11302-017-9593-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842154/
https://www.ncbi.nlm.nih.gov/pubmed/29164451
http://dx.doi.org/10.1007/s11302-017-9593-0

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