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The potential of P2X7 receptors as a therapeutic target, including inflammation and tumour progression
Seven P2X ion channel nucleotide receptor subtypes have been cloned and characterised. P2X7 receptors (P2X7R) are unusual in that there are extra amino acids in the intracellular C terminus. Low concentrations of ATP open cation channels sometimes leading to cell proliferation, whereas high concentr...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer Netherlands
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842154/ https://www.ncbi.nlm.nih.gov/pubmed/29164451 http://dx.doi.org/10.1007/s11302-017-9593-0 |