Functional transcriptomic annotation and protein–protein interaction network analysis identify NEK2, BIRC5, and TOP2A as potential targets in obese patients with luminal A breast cancer

PURPOSE: Although obesity is a risk factor for breast cancer, little effort has been made in the identification of druggable molecular alterations in obese–breast cancer patients. Tumors are controlled by their surrounding microenvironment, in which the adipose tissue is a main component. In this wo...

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Detalles Bibliográficos
Autores principales: Nuncia-Cantarero, Miriam, Martinez-Canales, Sandra, Andrés-Pretel, Fernando, Santpere, Gabriel, Ocaña, Alberto, Galan-Moya, Eva Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Preclinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842257/
https://www.ncbi.nlm.nih.gov/pubmed/29330624
http://dx.doi.org/10.1007/s10549-017-4652-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842257/
https://www.ncbi.nlm.nih.gov/pubmed/29330624
http://dx.doi.org/10.1007/s10549-017-4652-3

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