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Functional transcriptomic annotation and protein–protein interaction network analysis identify NEK2, BIRC5, and TOP2A as potential targets in obese patients with luminal A breast cancer
PURPOSE: Although obesity is a risk factor for breast cancer, little effort has been made in the identification of druggable molecular alterations in obese–breast cancer patients. Tumors are controlled by their surrounding microenvironment, in which the adipose tissue is a main component. In this wo...
Autores principales: | Nuncia-Cantarero, Miriam, Martinez-Canales, Sandra, Andrés-Pretel, Fernando, Santpere, Gabriel, Ocaña, Alberto, Galan-Moya, Eva Maria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842257/ https://www.ncbi.nlm.nih.gov/pubmed/29330624 http://dx.doi.org/10.1007/s10549-017-4652-3 |
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