Two models of inescapable stress increase tph2 mRNA expression in the anxiety-related dorsomedial part of the dorsal raphe nucleus

Expression of TPH2, the rate-limiting enzyme for brain serotonin synthesis, is elevated in the dorsal raphe nucleus (DR) of depressed suicide victims. One hypothesis is that this increase in TPH2 expression is stress-induced. Here, we used an established animal model to address whether exposure to a...

Descripción completa

Detalles Bibliográficos
Autores principales: Donner, Nina C., Kubala, Kenneth H., Hassell Jr., James E., Lieb, Margaret W., Nguyen, Kadi T., Heinze, Jared D., Drugan, Robert C., Maier, Steven F., Lowry, Christopher A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842308/
https://www.ncbi.nlm.nih.gov/pubmed/29520369
http://dx.doi.org/10.1016/j.ynstr.2018.01.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842308/
https://www.ncbi.nlm.nih.gov/pubmed/29520369
http://dx.doi.org/10.1016/j.ynstr.2018.01.003

Ejemplares similares