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Silencing of syndecan-binding protein enhances the inhibitory effect of tamoxifen and increases cellular sensitivity to estrogen

OBJECTIVE: Tamoxifen is used as a complementary treatment for estrogen receptor (ER)-positive breast cancer (BCa), but many patients developed resistance. The aim of this study was to examine the role of syndecan-binding protein (SDCBP) silencing in ER-positive BCa cells. METHODS: In MCF-7/T47D cell...

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Detalles Bibliográficos
Autores principales: Zhang, Jun, Qian, Xiaolong, Liu, Fangfang, Guo, Xiaojing, Gu, Feng, Fu, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Anti-Cancer Association 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842332/
https://www.ncbi.nlm.nih.gov/pubmed/29545966
http://dx.doi.org/10.20892/j.issn.2095-3941.2017.0122