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Silencing of syndecan-binding protein enhances the inhibitory effect of tamoxifen and increases cellular sensitivity to estrogen
OBJECTIVE: Tamoxifen is used as a complementary treatment for estrogen receptor (ER)-positive breast cancer (BCa), but many patients developed resistance. The aim of this study was to examine the role of syndecan-binding protein (SDCBP) silencing in ER-positive BCa cells. METHODS: In MCF-7/T47D cell...
Autores principales: | Zhang, Jun, Qian, Xiaolong, Liu, Fangfang, Guo, Xiaojing, Gu, Feng, Fu, Li |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Chinese Anti-Cancer Association
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842332/ https://www.ncbi.nlm.nih.gov/pubmed/29545966 http://dx.doi.org/10.20892/j.issn.2095-3941.2017.0122 |
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