EGFR tyrosine kinase inhibitor HS-10182 increases radiation sensitivity in non-small cell lung cancers with EGFR T790M mutation

OBJECTIVE: To investigate the potential of HS-10182, a second-generation epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI), as a radiosensitizer in non-small cell lung cancer (NSCLC). METHODS: Two cell lines of NSCLCs, A549 that possesses wild-type (WT) EGFRs and H1975 that posse...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Yang, Wang, Youyou, Zhao, Lujun, Wang, Ping, Sun, Jifeng, Bao, Rudi, Li, Chenghai, Liu, Ningbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Anti-Cancer Association 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842333/
https://www.ncbi.nlm.nih.gov/pubmed/29545967
http://dx.doi.org/10.20892/j.issn.2095-3941.2017.0118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842333/
https://www.ncbi.nlm.nih.gov/pubmed/29545967
http://dx.doi.org/10.20892/j.issn.2095-3941.2017.0118

Ejemplares similares