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EGFR tyrosine kinase inhibitor HS-10182 increases radiation sensitivity in non-small cell lung cancers with EGFR T790M mutation

OBJECTIVE: To investigate the potential of HS-10182, a second-generation epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI), as a radiosensitizer in non-small cell lung cancer (NSCLC). METHODS: Two cell lines of NSCLCs, A549 that possesses wild-type (WT) EGFRs and H1975 that posse...

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Detalles Bibliográficos
Autores principales:	Chen, Yang, Wang, Youyou, Zhao, Lujun, Wang, Ping, Sun, Jifeng, Bao, Rudi, Li, Chenghai, Liu, Ningbo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Chinese Anti-Cancer Association 2018
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842333/ https://www.ncbi.nlm.nih.gov/pubmed/29545967 http://dx.doi.org/10.20892/j.issn.2095-3941.2017.0118

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