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Key design considerations for adaptive clinical trials: a primer for clinicians

This article reviews important considerations for researchers who are designing adaptive clinical trials. These differ from conventional clinical trials because they allow and even enforce continual modifications to key components of trial design while data are being collected. This innovative appro...

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Detalles Bibliográficos
Autores principales: Thorlund, Kristian, Haggstrom, Jonas, Park, Jay JH, Mills, Edward J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group Ltd. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842365/
https://www.ncbi.nlm.nih.gov/pubmed/29519932
http://dx.doi.org/10.1136/bmj.k698