Synthesis and cytotoxic evaluation of some novel quinoxalinedione diarylamide sorafenib analogues

A series of novel sorafenib analogues containing a quinoxalinedione ring and amide linker were synthesized. A total of 9 novel compounds in 6 synthetic steps were synthesized. Briefly, the amino group of p-aminophenol was first protected which then followed by O-arylation with 5-chloro-2-nitroanilin...

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Detalles Bibliográficos
Autores principales: Khandan, Mojtaba, Sadeghian-Rizi, Sedighe, Khodarahmi, Ghadamali, Hassanzadeh, Farshid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842488/
https://www.ncbi.nlm.nih.gov/pubmed/29606971
http://dx.doi.org/10.4103/1735-5362.223802

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842488/
https://www.ncbi.nlm.nih.gov/pubmed/29606971
http://dx.doi.org/10.4103/1735-5362.223802

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