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Transependymal Cerebrospinal Fluid Flow: Opportunity for Drug Delivery?
Drug delivery to the central nervous system (CNS) is complicated by the blood-brain barrier. As a result, many agents that are found to be potentially effective at their site of action cannot be sufficiently or effectively delivered to the CNS and therefore have been discarded and not developed furt...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842497/ https://www.ncbi.nlm.nih.gov/pubmed/28455692 http://dx.doi.org/10.1007/s12035-017-0501-y |