Huntington Disease as a Neurodevelopmental Disorder and Early Signs of the Disease in Stem Cells

Huntington disease (HD) is a dominantly inherited disorder caused by a CAG expansion mutation in the huntingtin (HTT) gene, which results in the HTT protein that contains an expanded polyglutamine tract. The adult form of HD exhibits a late onset of the fully symptomatic phase. However, there is als...

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Detalles Bibliográficos
Autores principales: Wiatr, Kalina, Szlachcic, Wojciech J., Trzeciak, Marta, Figlerowicz, Marek, Figiel, Maciej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842500/
https://www.ncbi.nlm.nih.gov/pubmed/28497201
http://dx.doi.org/10.1007/s12035-017-0477-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842500/
https://www.ncbi.nlm.nih.gov/pubmed/28497201
http://dx.doi.org/10.1007/s12035-017-0477-7

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