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Allosteric Inhibition of Serotonin 5-HT(7) Receptors by Zinc Ions

The allosteric regulation of G protein-coupled receptors (GPCRs) is a well-known phenomenon, but there are only a few examples of allosteric modulation within the metabotropic serotonergic receptor family. Recently, we described zinc non-competitive interactions toward agonist binding at serotonin 5...

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Detalles Bibliográficos
Autores principales: Satała, Grzegorz, Duszyńska, Beata, Lenda, Tomasz, Nowak, Gabriel, Bojarski, Andrzej J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842505/
https://www.ncbi.nlm.nih.gov/pubmed/28455702
http://dx.doi.org/10.1007/s12035-017-0536-0