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GABA(B) receptor regulates proliferation in the high-grade chondrosarcoma cell line OUMS-27 via apoptotic pathways

BACKGROUND: High-grade chondrosarcoma, which has a high incidence of local recurrence and pulmonary metastasis despite surgical resection, is associated with poor prognosis. Therefore, new and effective adjuvant therapies are urgently required for this disease. Gamma-aminobutyric acid (GABA), which...

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Detalles Bibliográficos
Autores principales: Kanbara, Kiyoto, Otsuki, Yoshinori, Watanabe, Masahito, Yokoe, Syunichi, Mori, Yoshiaki, Asahi, Michio, Neo, Masashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842535/
https://www.ncbi.nlm.nih.gov/pubmed/29514603
http://dx.doi.org/10.1186/s12885-018-4149-4