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An information-theoretic approach to the modeling and analysis of whole-genome bisulfite sequencing data

BACKGROUND: DNA methylation is a stable form of epigenetic memory used by cells to control gene expression. Whole genome bisulfite sequencing (WGBS) has emerged as a gold-standard experimental technique for studying DNA methylation by producing high resolution genome-wide methylation profiles. Stati...

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Detalles Bibliográficos
Autores principales: Jenkinson, Garrett, Abante, Jordi, Feinberg, Andrew P., Goutsias, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842653/
https://www.ncbi.nlm.nih.gov/pubmed/29514626
http://dx.doi.org/10.1186/s12859-018-2086-5