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Glutamine Enhances the Hypoglycemic Effect of Insulin in L6 Cells via Phosphatidylinositol-3-Kinase (PI3K)/Protein Kinase B (AKT)/Glucose Transporter 4 (GLUT4) Signaling Pathway

BACKGROUND: Diabetes mellitus (DM) is characterized by a decreased blood level of glutamine (Gln), which may contribute to the disturbance in the effect of insulin on skeletal muscle. Therefore, it is crucial to study how to improve the effect of insulin on skeletal muscle by increasing Gln. In the...

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Detalles Bibliográficos
Autores principales: Wang, Caijuan, Deng, Yujiao, Yue, Yenan, Chen, Wenting, Zhang, Yu, Shi, Guifang, Wu, Zhongming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842660/
https://www.ncbi.nlm.nih.gov/pubmed/29491345
http://dx.doi.org/10.12659/MSM.909011