Targeted co-delivery of Beclin 1 siRNA and FTY720 to hepatocellular carcinoma by calcium phosphate nanoparticles for enhanced anticancer efficacy

PURPOSE: FTY720, known as fingolimod, is a new immunosuppressive agent with effective anticancer properties. Although it was recently confirmed that FTY720 inhibits cancer cell proliferation, FTY720 can also induce protective autophagy and reduce cytotoxicity. Blocking autophagy with Beclin 1 siRNA...

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Detalles Bibliográficos
Autores principales: Wu, Jun-Yi, Wang, Zhong-Xia, Zhang, Guang, Lu, Xian, Qiang, Guang-Hui, Hu, Wei, Ji, An-Lai, Wu, Jun-Hua, Jiang, Chun-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842779/
https://www.ncbi.nlm.nih.gov/pubmed/29551896
http://dx.doi.org/10.2147/IJN.S156328

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842779/
https://www.ncbi.nlm.nih.gov/pubmed/29551896
http://dx.doi.org/10.2147/IJN.S156328

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