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Do senescence markers correlate in vitro and in situ within individual human donors?

Little is known on how well senescence markers in vitro and in situ correlate within individual donors. We studied correlations between the same and different in vitro markers. Furthermore, we tested correlations between in vitro markers with in situ p16INK4a positivity. From 100 donors (20-91 years...

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Detalles Bibliográficos
Autores principales: Waaijer, Mariëtte E.C., Gunn, David A., van Heemst, Diana, Slagboom, P. Eline, Sedivy, John M., Dirks, Roeland W., Tanke, Hans J., Westendorp, Rudi G.J., Maier, Andrea B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842854/
https://www.ncbi.nlm.nih.gov/pubmed/29500330
http://dx.doi.org/10.18632/aging.101389