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Content uniformity of quartered hydrocortisone tablets in comparison with mini-tablets for paediatric dosing

OBJECTIVES: Children requiring cortisol replacement therapy are often prescribed hydrocortisone doses of 2.5 mg, but as this is commercially unavailable 10 mg tablets, with functional break lines, are split commonly in an attempt to deliver the correct dose. This study aimed to determine the dose va...

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Detalles Bibliográficos
Autores principales: Madathilethu, Jude, Roberts, Matthew, Peak, Matthew, Blair, Joanne, Prescott, Rebecca, Ford, James L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843003/
https://www.ncbi.nlm.nih.gov/pubmed/29637186
http://dx.doi.org/10.1136/bmjpo-2017-000198