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Frazzled can act through distinct molecular pathways in epithelial cells to regulate motility, apical constriction, and localisation of E-Cadherin

Netrin receptors of the DCC/NEO/UNC-40/Frazzled family have well established roles in cell migration and axon guidance but can also regulate epithelial features such as adhesion, polarity and adherens junction (AJ) stability. Previously, we have shown that overexpression of Drosophila Frazzled (Fra)...

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Detalles Bibliográficos
Autores principales: Golenkina, Sofia, Chaturvedi, Vishal, Saint, Robert, Murray, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843272/
https://www.ncbi.nlm.nih.gov/pubmed/29518139
http://dx.doi.org/10.1371/journal.pone.0194003