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Human dengue virus serotype 2 neutralizing antibodies target two distinct quaternary epitopes

Dengue virus (DENV) infection causes dengue fever, dengue hemorrhagic fever and dengue shock syndrome. It is estimated that a third of the world’s population is at risk for infection, with an estimated 390 million infections annually. Dengue virus serotype 2 (DENV2) causes severe epidemics, and the...

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Detalles Bibliográficos
Autores principales: Gallichotte, Emily N., Baric, Thomas J., Yount, Boyd L., Widman, Douglas G., Durbin, Anna, Whitehead, Steve, Baric, Ralph S., de Silva, Aravinda M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843351/
https://www.ncbi.nlm.nih.gov/pubmed/29481552
http://dx.doi.org/10.1371/journal.ppat.1006934