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Genetic mechanisms of Coxiella burnetii lipopolysaccharide phase variation

Coxiella burnetii is an intracellular pathogen that causes human Q fever, a disease that normally presents as a severe flu-like illness. Due to high infectivity and disease severity, the pathogen is considered a risk group 3 organism. Full-length lipopolysaccharide (LPS) is required for full virulen...

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Detalles Bibliográficos
Autores principales: Beare, Paul A., Jeffrey, Brendan M., Long, Carrie M., Martens, Craig M., Heinzen, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843353/
https://www.ncbi.nlm.nih.gov/pubmed/29481553
http://dx.doi.org/10.1371/journal.ppat.1006922