MYC is not detected in highly proliferating normal spermatogonia but is coupled with CIP2A in testicular cancers

High MYC expression is linked to proliferative activity in most normal tissues and in cancer. MYC also supports self-renewal and proliferation of many types of tissue progenitor cells. Cancerous inhibitor of PP2A (CIP2A) promotes MYC phosphorylation and activity during intestinal crypt regeneration...

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Detalles Bibliográficos
Autores principales: Ventelä, Sami, Mäkelä, Juho-Antti, Sears, Rosalie C, Toppari, Jorma, Westermarck, Jukka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843371/
https://www.ncbi.nlm.nih.gov/pubmed/29527532

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843371/
https://www.ncbi.nlm.nih.gov/pubmed/29527532

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