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MYC is not detected in highly proliferating normal spermatogonia but is coupled with CIP2A in testicular cancers
High MYC expression is linked to proliferative activity in most normal tissues and in cancer. MYC also supports self-renewal and proliferation of many types of tissue progenitor cells. Cancerous inhibitor of PP2A (CIP2A) promotes MYC phosphorylation and activity during intestinal crypt regeneration...
Autores principales: | Ventelä, Sami, Mäkelä, Juho-Antti, Sears, Rosalie C, Toppari, Jorma, Westermarck, Jukka |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843371/ https://www.ncbi.nlm.nih.gov/pubmed/29527532 |
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