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miR-15a represses cancer cell migration and invasion under conditions of hypoxia by targeting and downregulating Bcl-2 expression in human osteosarcoma cells

Osteosarcoma is a common, high-risk primary bone malignancy that mostly affects the younger population. There has been no marked improvement in the clinical outcomes of osteosarcoma patients to date, and cancer recurrence and metastasis are common in high-grade osteosarcoma. Therefore, identifying n...

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Detalles Bibliográficos
Autores principales: Leng, Jiali, Song, Qingxu, Zhao, Yuguang, Wang, Zhenyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843390/
https://www.ncbi.nlm.nih.gov/pubmed/29484432
http://dx.doi.org/10.3892/ijo.2018.4285