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Dna is a New Target of Parp3

Most members of the poly(ADP-ribose)polymerase family, PARP family, have a catalytic activity that involves the transfer of ADP-ribose from a beta-NAD+-molecule to protein acceptors. It was recently discovered by Talhaoui et al. that DNA-dependent PARP1 and PARP2 can also modify DNA. Here, we demons...

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Detalles Bibliográficos
Autores principales: Belousova, E. A., Ishchenko, А. A., Lavrik, O. I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843604/
https://www.ncbi.nlm.nih.gov/pubmed/29520010
http://dx.doi.org/10.1038/s41598-018-22673-3