Modulating the water channel AQP4 alters miRNA expression, astrocyte connectivity and water diffusion in the rodent brain

Aquaporins (AQPs) facilitate water diffusion through the plasma membrane. Brain aquaporin-4 (AQP4) is present in astrocytes and has critical roles in normal and disease physiology. We previously showed that a 24.9% decrease in AQP4 expression after in vivo silencing resulted in a 45.8% decrease in t...

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Detalles Bibliográficos
Autores principales: Jullienne, Amandine, Fukuda, Andrew M., Ichkova, Aleksandra, Nishiyama, Nina, Aussudre, Justine, Obenaus, André, Badaut, Jérôme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843607/
https://www.ncbi.nlm.nih.gov/pubmed/29520011
http://dx.doi.org/10.1038/s41598-018-22268-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843607/
https://www.ncbi.nlm.nih.gov/pubmed/29520011
http://dx.doi.org/10.1038/s41598-018-22268-y

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