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Genetic and metabolic regulation of Mycobacterium tuberculosis acid growth arrest
Mycobacterium tuberculosis (Mtb) senses and adapts to acidic environments during the course of infection. Acidic pH-dependent adaptations include the induction of metabolic genes associated with anaplerosis and growth arrest on specific carbon sources. Here we report that deletion of isocitrate lyas...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843633/ https://www.ncbi.nlm.nih.gov/pubmed/29520087 http://dx.doi.org/10.1038/s41598-018-22343-4 |