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Rapid and transient oxygen consumption increase following acute HDAC/KDAC inhibition in Drosophila tissue

Epigenetic deregulation, such as the reduction of histone acetylation levels, is thought to be causally linked to various maladies associated with aging. Consequently, histone deacetylase inhibitors are suggested to serve as epigenetic therapy by increasing histone acetylation. However, previous wor...

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Detalles Bibliográficos
Autores principales: Becker, Lore, Nogueira, Melanie Schmitt, Klima, Caroline, de Angelis, Martin Hrabe, Peleg, Shahaf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843646/
https://www.ncbi.nlm.nih.gov/pubmed/29520020
http://dx.doi.org/10.1038/s41598-018-22674-2