Aberrant GlyRS-HDAC6 interaction linked to axonal transport deficits in Charcot-Marie-Tooth neuropathy

Dominant mutations in glycyl-tRNA synthetase (GlyRS) cause a subtype of Charcot-Marie-Tooth neuropathy (CMT2D). Although previous studies have shown that GlyRS mutants aberrantly interact with Nrp1, giving insight into the disease’s specific effects on motor neurons, these cannot explain length-depe...

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Detalles Bibliográficos
Autores principales: Mo, Zhongying, Zhao, Xiaobei, Liu, Huaqing, Hu, Qinghua, Chen, Xu-Qiao, Pham, Jessica, Wei, Na, Liu, Ze, Zhou, Jiadong, Burgess, Robert W., Pfaff, Samuel L., Caskey, C. Thomas, Wu, Chengbiao, Bai, Ge, Yang, Xiang-Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843656/
https://www.ncbi.nlm.nih.gov/pubmed/29520015
http://dx.doi.org/10.1038/s41467-018-03461-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843656/
https://www.ncbi.nlm.nih.gov/pubmed/29520015
http://dx.doi.org/10.1038/s41467-018-03461-z

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