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An accurate and robust imputation method scImpute for single-cell RNA-seq data

The emerging single-cell RNA sequencing (scRNA-seq) technologies enable the investigation of transcriptomic landscapes at the single-cell resolution. ScRNA-seq data analysis is complicated by excess zero counts, the so-called dropouts due to low amounts of mRNA sequenced within individual cells. We...

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Detalles Bibliográficos
Autores principales: Li, Wei Vivian, Li, Jingyi Jessica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843666/
https://www.ncbi.nlm.nih.gov/pubmed/29520097
http://dx.doi.org/10.1038/s41467-018-03405-7