NPM1 Mutation Analysis in Acute Myeloid Leukemia: Comparison of Three Techniques - Sanger Sequencing, Pyrosequencing, and Real-Time Polymerase Chain Reaction

OBJECTIVE: Nucleophosmin-1 (NPM1) mutations have prognostic importance in acute myeloid leukemia (AML) patients with intermediate-risk karyotype at diagnosis. Approximately 30% of newly diagnosed cytogenetically normal AML (CN-AML) patients harbor the NPM1 mutation in India. In this study we compare...

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Detalles Bibliográficos
Autores principales: Kumar, Dushyant, Mehta, Anurag, Panigrahi, Manoj Kumar, Nath, Sukanta, Saikia, Kandarpa Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843774/
https://www.ncbi.nlm.nih.gov/pubmed/29129825
http://dx.doi.org/10.4274/tjh.2017.0095

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843774/
https://www.ncbi.nlm.nih.gov/pubmed/29129825
http://dx.doi.org/10.4274/tjh.2017.0095

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