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Improved GMP-compliant multi-dose production and quality control of 6-[(18)F]fluoro-L-DOPA

BACKGROUND: 6-[(18)F]Fluoro-L-3,4-dihydroxyphenylalanine (FDOPA) is a frequently used radiopharmaceutical for detecting neuroendocrine and brain tumors and for the differential diagnosis of Parkinson’s disease. To meet the demand for FDOPA, a high-yield GMP-compliant production method is required. T...

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Detalles Bibliográficos
Autores principales: Luurtsema, G., Boersma, H. H., Schepers, M., de Vries, A. M. T., Maas, B., Zijlma, R., de Vries, E. F. J., Elsinga, P. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843807/
https://www.ncbi.nlm.nih.gov/pubmed/29564384
http://dx.doi.org/10.1186/s41181-016-0009-1