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Improved GMP-compliant multi-dose production and quality control of 6-[(18)F]fluoro-L-DOPA
BACKGROUND: 6-[(18)F]Fluoro-L-3,4-dihydroxyphenylalanine (FDOPA) is a frequently used radiopharmaceutical for detecting neuroendocrine and brain tumors and for the differential diagnosis of Parkinson’s disease. To meet the demand for FDOPA, a high-yield GMP-compliant production method is required. T...
Autores principales: | Luurtsema, G., Boersma, H. H., Schepers, M., de Vries, A. M. T., Maas, B., Zijlma, R., de Vries, E. F. J., Elsinga, P. H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843807/ https://www.ncbi.nlm.nih.gov/pubmed/29564384 http://dx.doi.org/10.1186/s41181-016-0009-1 |
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