Improved radiolabeling of DOTATOC with trivalent radiometals for clinical application by addition of ethanol

BACKGROUND: Typically, metal-based radiopharmaceuticals are synthesized in aqueous solutions with no or low ethanol content. Labeling yields are defined by temperature, period of labeling, amount of precursor, pH etc. As recently observed, radiolabeling yields (RCY) seem to increase in the presence...

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Detalles Bibliográficos
Autores principales: Eppard, Elisabeth, Pèrez-Malo, Marylaine, Rösch, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843808/
https://www.ncbi.nlm.nih.gov/pubmed/29564383
http://dx.doi.org/10.1186/s41181-016-0010-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843808/
https://www.ncbi.nlm.nih.gov/pubmed/29564383
http://dx.doi.org/10.1186/s41181-016-0010-8

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