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Improved radiolabeling of DOTATOC with trivalent radiometals for clinical application by addition of ethanol
BACKGROUND: Typically, metal-based radiopharmaceuticals are synthesized in aqueous solutions with no or low ethanol content. Labeling yields are defined by temperature, period of labeling, amount of precursor, pH etc. As recently observed, radiolabeling yields (RCY) seem to increase in the presence...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer International Publishing
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843808/ https://www.ncbi.nlm.nih.gov/pubmed/29564383 http://dx.doi.org/10.1186/s41181-016-0010-8 |