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Optimizing labelling conditions of (213)Bi-DOTATATE for preclinical applications of peptide receptor targeted alpha therapy

BACKGROUND: (213)Bismuth ((213)Bi, T(1/2) = 45.6 min) is one of the most frequently used α-emitters in cancer research. High specific activity radioligands are required for peptide receptor radionuclide therapy. The use of generators containing less than 222 MBq (225)Ac (actinium), due to limited av...

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Detalles Bibliográficos
Autores principales: Chan, Ho Sze, de Blois, Erik, Konijnenberg, Mark W., Morgenstern, Alfred, Bruchertseifer, Frank, Norenberg, Jeffrey P., Verzijlbergen, Fred J., de Jong, Marion, Breeman, Wouter A. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843812/
https://www.ncbi.nlm.nih.gov/pubmed/29564386
http://dx.doi.org/10.1186/s41181-016-0014-4