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New protein deposition tracers in the pipeline

Traditional nuclear medicine ligands were designed to target cellular receptors or transporters with a binding pocket and a defined structure–activity relationship. More recently, tracers have been developed to target pathological protein aggregations, which have less well-defined structure–activity...

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Detalles Bibliográficos
Autores principales: Jovalekic, Aleksandar, Koglin, Norman, Mueller, Andre, Stephens, Andrew W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843813/
https://www.ncbi.nlm.nih.gov/pubmed/29564387
http://dx.doi.org/10.1186/s41181-016-0015-3