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Effects of exendin-4 on the intrarenal renin-angiotensin system and interstitial fibrosis in unilateral ureteral obstruction mice: Exendin-4 and unilateral ureteral obstruction

OBJECTIVE: The objective of this article is to investigate the renoprotecive effects of exendin-4 in a mouse model of unilateral ureteral obstruction (UUO) and explore the putative mechanisms. METHODS: Male Balbc mice underwent sham operation or UUO surgery, and then received intraperitoneal injecti...

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Detalles Bibliográficos
Autores principales: Le, Ying, Zheng, Zongji, Xue, Junyu, Cheng, Mengling, Guan, Meiping, Xue, Yaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843888/
https://www.ncbi.nlm.nih.gov/pubmed/27913661
http://dx.doi.org/10.1177/1470320316677918