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NG2 antigen is involved in leukemia invasiveness and central nervous system infiltration in MLL-rearranged infant B-ALL

Mixed-lineage leukemia (MLL)-rearranged (MLLr) infant B-cell acute lymphoblastic leukemia (iMLLr-B-ALL) has a dismal prognosis and is associated with a pro-B/mixed phenotype, therapy refractoriness and frequent central nervous system (CNS) disease/relapse. Neuron-glial antigen 2 (NG2) is specificall...

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Detalles Bibliográficos
Autores principales: Prieto, C, López-Millán, B, Roca-Ho, H, Stam, R W, Romero-Moya, D, Rodríguez-Baena, F J, Sanjuan-Pla, A, Ayllón, V, Ramírez, M, Bardini, M, De Lorenzo, P, Valsecchi, M G, Stanulla, M, Iglesias, M, Ballerini, P, Carcaboso, Á M, Mora, J, Locatelli, F, Bertaina, A, Padilla, L, Carlos Rodríguez-Manzaneque, J, Bueno, C, Menéndez, P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843903/
https://www.ncbi.nlm.nih.gov/pubmed/28943635
http://dx.doi.org/10.1038/leu.2017.294