Detection of PRMT1 inhibitors with stopped flow fluorescence

Protein arginine methyltransferases (PRMTs) are crucial epigenetic regulators in eukaryotic organisms that serve as histone writers for chromatin remodeling. PRMTs also methylate a variety of non-histone protein substrates to modulate their function and activity. The development of potent PRMT inhib...

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Detalles Bibliográficos
Autores principales: Qian, Kun, Hu, Hao, Xu, Hui, Zheng, Y George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843908/
https://www.ncbi.nlm.nih.gov/pubmed/29535867
http://dx.doi.org/10.1038/s41392-018-0009-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843908/
https://www.ncbi.nlm.nih.gov/pubmed/29535867
http://dx.doi.org/10.1038/s41392-018-0009-6

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