LY3045697: Results from two randomized clinical trials of a novel inhibitor of aldosterone synthase

INTRODUCTION: LY3045697 is a potent and selective aldosterone synthase (CYP11B2) inhibitor that was developed as a safer alternative to mineralocorticoid receptor antagonists. Effects of LY3045697 on aldosterone and cortisol synthesis, as well as potassium ion homeostasis, were evaluated in two clin...

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Detalles Bibliográficos
Autores principales: Sloan-Lancaster, Joanne, Raddad, Eyas, Flynt, Amy, Jin, Yan, Voelker, James, Miller, Jeffrey W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843917/
https://www.ncbi.nlm.nih.gov/pubmed/28814143
http://dx.doi.org/10.1177/1470320317717883

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843917/
https://www.ncbi.nlm.nih.gov/pubmed/28814143
http://dx.doi.org/10.1177/1470320317717883

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