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LY3045697: Results from two randomized clinical trials of a novel inhibitor of aldosterone synthase
INTRODUCTION: LY3045697 is a potent and selective aldosterone synthase (CYP11B2) inhibitor that was developed as a safer alternative to mineralocorticoid receptor antagonists. Effects of LY3045697 on aldosterone and cortisol synthesis, as well as potassium ion homeostasis, were evaluated in two clin...
Autores principales: | Sloan-Lancaster, Joanne, Raddad, Eyas, Flynt, Amy, Jin, Yan, Voelker, James, Miller, Jeffrey W |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843917/ https://www.ncbi.nlm.nih.gov/pubmed/28814143 http://dx.doi.org/10.1177/1470320317717883 |
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